401. Senior Seminar
Angiogenesis, the growth of new blood vessels, has great clinical significance in the treatment for conditions such as cancer, heart disease and wound healing. There are numerous positive and inhibitory angiogenic agents. The seminar will focus on various physiological and pathological conditions involving angiogenesis and examine how different endogenous and exogenous agents produce their effects by acting on many different pathways in the vascular tissue, the extracellular matrix and in the endothelial cells via a wide array of growth factors and other agents on the receptors, the enzymes and the angiogenic genes.